Affective temperaments and neurocognitive functioning in bipolar disorder

Neurocognitive impairment in euthymic patients with bipolar affective disorder.

BACKGROUND Persistent impairments in neurocognitive function have been described in patients with bipolar disorder whose disease is in remission. However, methodological issues such as the effect of residual mood symptoms and hypercortisolaemia may confound such studies. AIMS To assess neurocognitive functioning in prospectively verified euthymic patients with bipolar disorder. METHOD Sixty...

The Relationship Between Neurocognitive Functioning and Occupational Functioning in Bipolar Disorder: A Literature Review

Neurocognitive impairment in Bipolar Disorder (BD) has been widely reported, even during remission. Neurocognitive impairment has been identified as a contributing factor towards unfavourable psychosocial functioning within this population. The objective of this review was to investigate the association between neurocognitive impairment and occupational functioning in BD. A literature review of...

How Do Affective Temperaments Develop Into Bipolar Disorders?

Affective temperaments are considered to be antecedents or sub-syndromal manifestations of bipolar disorders. It is, however, unknown how these temperaments develop into bipolar disorders. We hypothesize that: [1] just before the onset of bipolar disorder, the left medial frontal gyrus (MFG) of cyclothymic and/or hyperthymic healthy subjects may degenerate and shrink in volume concomitantly wit...

Psychosocial Functioning in Depressive Patients: A Comparative Study between Major Depressive Disorder and Bipolar Affective Disorder

Introduction. Major depressive disorder (MDD) and bipolar affective disorder (BAD) are among the leading causes of disability. These are often associated with widespread impairments in all domains of functioning including relational, occupational, and social. The main aim of the study was to examine and compare nature and extent of psychosocial impairment of patients with MDD and BAD during dep...

Bipolar affective disorder